2. Signaling Pathways
  3. Immunology/Inflammation
  4. NO Synthase
  5. iNOS Isoform
  6. iNOS Agonist

iNOS Agonist

iNOS Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-128671
    6-​Thioinosine
    		Agonist 99.31%
    6-Thioinosine (6TI) is a purine antimetabolite and an anti-adipogenic agent. 6-Thioinosine reduces the mRNA levels of PPARγ and C/EBPα and downregulates the mRNA levels of PPARγ target genes (LPL, CD36, aP2, and LXRα). 6-Thioinosine exerts its anti-adipogenic effects by downregulating PPARγ through JNK-dependent iNOS upregulation. 6-Thioinosine can be used to study adipocyte dysfunction.